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The difference between proper refrigeration and leaving a vial on a bathroom counter for a few hours can mean weeks of lost shelf life

Why this matters: Wegovy is the only GLP-1 with FDA approval for both weight loss AND cardiovascular risk reduction (heart attack/stroke prevention)

Once you open an Ozempic pen, it can be kept at room temperature (59F86F) or in the fridge for up to 56 days

Stimulant laxatives, such as Dulcolax, senna/sennosides, and Senokot (Bisacodyl)

You should not change your dosing regimen or stop taking Ozempic as prescribed without discussing with your provider first

Dedicated factorial trials would clarify whether these complementary pathways produce additive, supra-additive, or attenuated effects on hard outcomes